Long term outcome of twin-twin transfusion syndrome.

Long-term neurodevelopmental outcome in twin-to-twin transfusion syndrome.

OBJECTIVE The purpose of this study was to determine the long-term neurodevelopmental outcome in children after twin-to-twin transfusion syndrome. STUDY DESIGN Maternal and neonatal medical records of all twin-to-twin transfusion syndrome patients who were admitted to our center between 1990 and 1998 were reviewed. Neurologic and mental development at school age was assessed during a home vis...

Twin-to-twin transfusion syndrome: from placental anastomoses to long-term neurodevelopmental outcome

Cerebral injury and neurodevelopmental impairment after amnioreduction versus laser surgery in twin-twin transfusion syndrome: a systematic review and meta-analysis.

OBJECTIVE To estimate the odds of severe cerebral injury and long-term neurodevelopmental impairment in monochorionic twins treated with amnioreduction versus laser surgery for twin-twin transfusion syndrome. METHODS A systematic review and meta-analysis of studies on cerebral injury and long-term impairment after amnioreduction versus laser surgery were conducted. Odds ratios (OR) with their...

Postnatal MRI Brain in Infants Treated for Twin-Twin Transfusion Syndrome.

Untreated twin-twin transfusion syndrome (TTTS) is associated with significant mortality and neurological impairment. Fetoscopic laser surgery (FLS) is the treatment of choice. We sought to assess intracranial abnormalities in TTTS twins following treatment. In this prospective, blinded study MRI scans were performed on 3 groups; (1) monochorionic diamniotic (MCDA) twins with TTTS who had under...

I-40: Ultrasound in Multiple Pregnancy

Ultrasound has revolutioned the care of women carring twins. First trimester evaluation is the best time to determine chorioniocity and amnioniocity in multiple gestations. First trimester diagnosis is based on the number of gestational sacs, amnions and yolk sacs. Growth rate in multiple multiple gestations during the fist and early second trimesters parallels the growth rate of singleton preg...

Twin-twin transfusion syndrome: an update.

Twin-twin transfusion syndrome leads to high rates of perinatal morbidity and mortality due to its poorly understood etiology and difficult diagnosing and treatment. Current therapies are suboptimal and have not been tested through randomized controlled trials. Parent counseling at the time of diagnosis includes informing on poor chance of double survival, relatively high chance of long term ne...